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Whiles-Lillig, Jennifer

 
 

Jennifer Whiles-Lillig, Assistant Professor, Department of Chemistry

Recent Submissions

  • Structural Evaluation of Phospholipid Bicelles for Solution-State Studies of Membrane-Associated Biomolecules 
    Glover, Kerney J.; Whiles-Lillig, Jennifer; Wu, Guohua; Yu, Nan-jun; Deems, Raymond; Struppe, Jochem O.; Stark, Ruth E.; Komives, Elizabeth A.; Vold, Regitze R. (Biophysical Journal, 2001-10)
    Several complementary physical techniques have been used to characterize the aggregate structures formed in solutions containing dimyristoylphosphatidylcholine (DMPC)/dihexanoylphosphatidylcholine (DHPC) at ratios of ≤ 0.5 ...
  • Orientation and Effects of Mastoparan X on Phospholipid Bicelles 
    Whiles-Lillig, Jennifer; Brasseur, Robert; Glover, Kerney J.; Melacini, Giuseppe; Komives, Elizabeth A.; Vold, Regitze R. (Biophysical Journal, 2001)
    Mastoparan X (MPX: INWKGIAAMAKKLL-NH2) belongs to a family of ionophoric peptides found in wasp venom. Upon binding to the membrane, MPX increases the cell’s permeability to cations leading to a disruption in the electrolyte ...
  • Acidic Phospholipid Bicelles: A Versatile Model Membrane System 
    Struppe, Jochem; Whiles-Lillig, Jennifer; Vold, R.R. (Biophysical Journal, 2000-01)
    With the aim of establishing acidic bicellar solutions as a useful membrane model system, we have used deuterium NMR spectroscopy to investigate the properties of dimyristoyl/dihexanoylphosphatidylcholine (DMPC/DHPC) bicelles ...
  • Orientation and Helical Conformation of a Tissue-specific Hunter-killer Peptide in Micelles 
    Plesniak, Leigh A.; Parducho, Jonathan I.; Ziebart, Angie; Geierstanger, Bernhard H; Whiles-Lillig, Jennifer; Melacini, Guiseppe; Jennings, Patricia A. (Protein Science, 2004)
    Hunter-killer peptides are chimeric synthetic peptides that selectively target specific cell types for an apoptotic death. These peptides, which are models for potential therapeutics, contain a homing sequence for ...
  • Methods for Studying Transmembrane Peptides in Bicelles: Consequences of Hydrophobic Mismatch and Peptide Sequence 
    Whiles-Lillig, Jennifer; Glover, Kerney J.; Vold, Regitze R.; Komives, Elizabeth A. (Journal of Magnetic Resonance, 2002)
    We have shown that bicelles prepared from dilauryl phosphatidylcholine (DLPC) and dipalmitoyl phosphatidylcholine (DPPC) align in a magnetic field under conditions similar to the more common dimyristoyl phosphatidylcholine ...